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At EMD Serono, Inc. our strength is our people!

About the Company

EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support systems to improve people's lives. The company has strong market positions in neurodegenerative diseases, MS and endocrinology. EMD Serono is also a leader in fertility treatments. With a clear focus on the patient and a leadership presence in the biopharmaceutical industry, EMD Serono's US footprint continues to grow, with more than 1000 employees around the country and fully integrated commercial, clinical and research operations in the company's home state of Massachusetts.

Description

EMD Serono is seeking to appoint a motivated and well qualified scientist for the Protein Engineering and Monoclonal Antibody Technologies (PEAT) group within New Biological Entities (NBE) Technologies. He/she will be responsible for the Monoclonal Antibody Engineering needs of the group and head up a laboratory staff of three with a potential to grow.

This individual will report to the Head of PEAT at their facility in suburban Boston and will be part of an energetic team in a key strategic area of the Discovery organization within EMD Serono. In this regard, he/she will play an important role in the overall responsibility of NBE Technologies for the discovery, optimization and progression of the Company's biotherapeutics discovery pipeline.

As Scientist - Antibody Engineering the incumbent will have responsibilities including, but not limited to, the following:

• Leading a group of scientist and technicians in the Monoclonal Antibody Engineering laboratory
• Assuming responsibility for the humanization and optimization of antibody candidates generated by hybridoma- or phage display-technology.
• Managing the group and taking responsibility for its projects by driving and coordinating his/her direct reports in achieving the specific objectives of the respective research projects.
• Advancing antibody technologies within his/her own group as well as influencing the strategies on current and future technologies.
• Representing the monoclonal antibody department in specific antibody project teams.
• Taking responsibility for defining requirements for research projects and identifying potential constraints and risks.
• Use of problem solving skills in evaluating issues, and monitoring and initiating corrective actions where necessary.
• Taking responsibility for proposing new projects or amendments to existing projects to the Head of PEAT in the US.

Qualifications

• The ideal candidate will have a Ph.D. in molecular biology, biochemistry, biotechnology or biological sciences.
• This individual will be a highly motivated scientist with a proven track record in antibody engineering and must have several years of post-doctoral experience in an academic or industry setting.
• A strong background in molecular biology, with extensive experience in antibody engineering, antibody expression and purification, and biochemical and biophysical methods for the analysis of antibodies is required. An interest to work part-time at the laboratory bench is desirable.
• Familiarity with antibody phage display technology and affinity maturation, and interpretation of computational modelling of antibody-antigen interactions would be useful. Further, experience in preclinical development of therapeutic antibodies is desirable.
• It is desired that the candidate demonstrate an aptitude to interact constructively with others across multiple cultural backgrounds in a dynamic matrix structure. He/she must have the ability to collaborate with colleagues throughout the organization in research functions i.e., bio-informatics, protein and cell sciences and structural biology and in corporate functions i.e., business development, intellectual property.
• Further to this the candidate will possess strong communication skills, both oral and written. He/she should be confident in presentation with parties both small and large.
• As leader of a group, the candidate must be committed to its members and foster a teamwork approach. This will partially be accomplished through the facilitation of a positive work environment. He/she should be skilled in motivating and coaching others as well as interacting well in a team.
• The candidate will be, above all, a proactive self-starter with a positive "can do" attitude. He/she will have demonstrated success in achieving goals, be strongly results oriented and have the ability to drive tasks through to completion.
• The incumbent will be required to focus on multiple issues at one time, and must have the ability to organise and direct diverse activities in a changing environment, often under time pressure.
• With a mature, self-confident and well-balanced personality, it is essential that the candidate also possess a high standard of ethical and intellectual integrity.
• Finally, the candidate must be strongly computer literate.

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EMD Serono 0900481