Brigham and Women’s Hospital (BWH) is internationally known as a leader in cutting-edge research and technology and its commitment to patient-centered care. BWH has a rich legacy of excellence and has been consistently recognized as one of America’s best hospitals by US News and World Report.
Responsibilities
GENERAL SUMMARY:
In collaboration with senior member of the research team, assist in projects to elucidate the in vitro and in vivo functions of dysregulated microRNAs in Huntington's disease (HD). Working under very general supervision, execute protocols involving a variety of routine and non-routine experiments at a professional level. Develop modification of existing techniques, as appropriate. Calculate, transcribe, and analyze data using statistical techniques.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
1. Perform routine and non-routine experiments, which are moderate to complex. (Experiments may include RT-PCR, western blot, immunohistochemistry, DNA & RNA isolation, purification and quantification, transformation and transfection.)
2. Mouse husbandry, breeding, tail vein injection, and behavioral observation.
3. Maintain long-term tissue cultures of mammalian cell lines, stem cells and culture of primary neuron. Monitor cell viability, proliferation and cytotoxicity (MTS, LDH assay).
4. Calculate, transcribe and analyze data using advanced statistical techniques.
5. Perform literature searches and help to prepare presentations.
6. Other duties as assigned.
Requirements
QUALIFICATIONS:
BS or Master in biology or related science. Good background in molecular biology, cell biology, and working experience with small animals. 1-2 years of experience at molecular level and in vivo small animal studies in neuroscience/cell biology is a plus. Previous experience with mice tail vein injection is preferred but not necessary.
SKILLS/ABILITIES/COMPETENCIES REQUIRED:
1. Sound analytical and organizational skills.
2. Good oral and written communication skills.
3. Ability to logically and effectively structure tasks and set priorities.
4. Ability to identify potential problems and trouble-shoot solutions.
5. Demonstrated ability to analyze data statistically and to logically present it.
SUPERVISORY RESPONSIBILITIES:
None
WORKING CONDITIONS:
Basic biomedical research lab.
Shift
Day Shift
To apply online, please submit your resume here:
https://careers.partners.org/psc/EA/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_CE.GBL?Page=HRS_CE_JOB_DTL&Action=A&SiteId=2&HRS_JOB_OPENING_ID=2194744
Brigham and Women’s Hospital is an EEO, AA and VEVRAA employer.
http://www.brighamandwomens.org/careers
- Location: Boston-On Campus/Longwood Area
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