Brigham and Women’s Hospital (BWH) is internationally known as a leader in cutting-edge research and technology and its commitment to patient-centered care. BWH has a rich legacy of excellence and has been consistently recognized as one of America’s best hospitals by US News and World Report.
GENERAL SUMMARY/ OVERVIEW STATEMENT:
The Respiratory Functional Genetics Laboratory focuses on biological functional evaluation of genetic variants associated with asthma and chronic obstructive pulmonary disease (COPD). The TRAII will be an active participant in experimental research and will have the opportunity to present his/her lab work. He/she will work independently, and perform non-routine, highly specialized molecular biology experiments. Also participate in the modification of research protocols.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
1) Independently performs molecular biology and cell biology procedures including but not limited to DNA and cDNA cloning, cell transfection, cell culture and reporter assay.
2) Responsible for the coordination of individual projects, including quality assurance, tracking laboratory supplies and scheduling to meet deadlines.
3) Independently performs experiments and analyzes results.
4) Prepares reagents, solutions and buffers for use in procedures.
5) Under supervision of Respiratory Functional Genetics Laboratory Director, establishes new and modifies existing research techniques.
7) All other duties as assigned
QUALIFICATIONS:
1) BS or BA required; MS degree preferred in Biological Science.
2) Minimum 1 year of relevant lab work experience.
3) Experience with molecular cloning, PCR, mini and maxi preparation plasmid, cell culture, transfection, western blot and immunofluorescence.
4) Experience with nuclear protein extraction, reporter assay and RNAi delivery is plus.
5) Experience with mouse models would be desirable.
SKILLS/ ABILITIES/ COMPETENCIES REQUIRED:
1) Ability to attend to detail and to be precise. Sound analytical and organizational skills.
2) Excellent written and verbal communication skills; must be able to thoroughly document experiments, protocols, and data. Must be able to logically structure tasks and set priorities.
3) Knowledge of cell biology and/or molecular biology typically obtained through a bachelors degree program in biology, molecular genetics, biochemistry, or laboratory science. Broad knowledge of scientific principles and laboratory techniques. Ability to identify potential problems, communicate and troubleshoot them effectively.
4) Must be able to operate and maintain delicate electronic equipment and safely use and dispose of toxic chemicals and biohazardous materials.
WORKING CONDITIONS:
Variety of laboratory/office settings. Exposure to toxic chemicals and biohazardous materials. Work may require odd hours to complete experiments.
To apply online, please submit your resume here:
https://careers.partners.org/psc/EA/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_CE.GBL?Page=HRS_CE_JOB_DTL&Action=A&SiteId=2&HRS_JOB_OPENING_ID=2195595
Brigham and Women’s Hospital is an EEO, AA and VEVRAA employer.
http://www.brighamandwomens.org/careers
- Location: Boston, MA
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